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  "Title": "Simulate single cell and spatial transcriptomics data",
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  "Date": "2023-08-26",
  "Author": "Qi Gao",
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  "Maintainer": "Qi Gao <qi.gao@duke.edu>",
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    "extra/citation.json",
    "extra/citation.txt",
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    "extra/GeneScape.html",
    "extra/manual.pdf",
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  "_realowner": "qigao1",
  "_cranurl": true,
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      "date": "2023-06-13"
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    "add_distort",
    "aggregate_expression",
    "assign_cell_types",
    "assign_tissue_types",
    "cell_position_simulation",
    "changeLibSize",
    "cumsum_cpp",
    "downSampleRead",
    "est_bound",
    "estimate_gamma",
    "estimate_lognormal",
    "estimate_nb",
    "estimate_zinb",
    "estimate_zip",
    "fcsim",
    "GeneScape_est",
    "GeneScape_par",
    "GeneScape_sim",
    "GeneScapeS_est",
    "GeneScapeS_sim",
    "inverse_logit",
    "knn_tissue_update",
    "knnassign",
    "rotate_pg",
    "rotate_sample",
    "sample_int",
    "sample_region_simulation",
    "scale_sample",
    "shift_sample",
    "sp_dist_euclidean_cpp",
    "spot_simulate",
    "tissue_region_simulation",
    "update_sample_region",
    "zinb_nll"
  ],
  "_help": [
    {
      "page": "add_distort",
      "title": "add_distort",
      "topics": [
        "add_distort"
      ]
    },
    {
      "page": "aggregate_expression",
      "title": "aggregate_expression",
      "topics": [
        "aggregate_expression"
      ]
    },
    {
      "page": "assign_cell_types",
      "title": "assign_cell_types",
      "topics": [
        "assign_cell_types"
      ]
    },
    {
      "page": "assign_tissue_types",
      "title": "assign_tissue_types",
      "topics": [
        "assign_tissue_types"
      ]
    },
    {
      "page": "cell_position_simulation",
      "title": "cell_position_simulation",
      "topics": [
        "cell_position_simulation"
      ]
    },
    {
      "page": "changeLibSize",
      "title": "changeLibSize This function modifies the simulated counts so that the total read count in each spot is the same as the example data.",
      "topics": [
        "changeLibSize"
      ]
    },
    {
      "page": "cumsum_cpp",
      "title": "cumsum_cpp This function calculates the cumulative sum (partial sum) of a vector.",
      "topics": [
        "cumsum_cpp"
      ]
    },
    {
      "page": "downSampleRead",
      "title": "downSampleRead This function uses down-sampling to obtain the reads in each spot.",
      "topics": [
        "downSampleRead"
      ]
    },
    {
      "page": "est_bound",
      "title": "est_bound",
      "topics": [
        "est_bound"
      ]
    },
    {
      "page": "estimate_gamma",
      "title": "estimate_gamma This function estimates gamma distribution shape and rate parameters.",
      "topics": [
        "estimate_gamma"
      ]
    },
    {
      "page": "estimate_lognormal",
      "title": "estimate_lognormal This function estimates estimate_lognormal distribution loc and scale parameters.",
      "topics": [
        "estimate_lognormal"
      ]
    },
    {
      "page": "estimate_nb",
      "title": "estimate_nb This function estimates negative binomial distribution mean and dispersion parameters.",
      "topics": [
        "estimate_nb"
      ]
    },
    {
      "page": "estimate_zinb",
      "title": "estimate_zinb This function estimates the mean, dispersion and zero inflation parameters in zero-inflated negative binomial distribution.",
      "topics": [
        "estimate_zinb"
      ]
    },
    {
      "page": "estimate_zip",
      "title": "estimate_zip",
      "topics": [
        "estimate_zip"
      ]
    },
    {
      "page": "fcsim",
      "title": "fcsim",
      "topics": [
        "fcsim"
      ]
    },
    {
      "page": "GeneScape_est",
      "title": "GeneScape_est",
      "topics": [
        "GeneScape_est"
      ]
    },
    {
      "page": "GeneScape_par",
      "title": "GeneScape_par",
      "topics": [
        "GeneScape_par"
      ]
    },
    {
      "page": "GeneScape_sim",
      "title": "GeneScape_sim",
      "topics": [
        "GeneScape_sim"
      ]
    },
    {
      "page": "GeneScapeS_est",
      "title": "GeneScapeS_est This function estimates distribution parameters from an example data.",
      "topics": [
        "GeneScapeS_est"
      ]
    },
    {
      "page": "GeneScapeS_sim",
      "title": "GeneScapeS_sim This function generates simulated data based on distribution parameters estimated from an example data.",
      "topics": [
        "GeneScapeS_sim"
      ]
    },
    {
      "page": "inverse_logit",
      "title": "inverse_logit This function is the inverse logit function.",
      "topics": [
        "inverse_logit"
      ]
    },
    {
      "page": "knn_tissue_update",
      "title": "knn_tissue_update",
      "topics": [
        "knn_tissue_update"
      ]
    },
    {
      "page": "knnassign",
      "title": "knnassign This function uses KNN sampling to simulate gradually changed tissue types.",
      "topics": [
        "knnassign"
      ]
    },
    {
      "page": "rotate_pg",
      "title": "rotate_pg",
      "topics": [
        "rotate_pg"
      ]
    },
    {
      "page": "rotate_sample",
      "title": "rotate_sample",
      "topics": [
        "rotate_sample"
      ]
    },
    {
      "page": "sample_int",
      "title": "sample_int This function samples integers from 1 to an upper limit integer value with equal probability without replacement.",
      "topics": [
        "sample_int"
      ]
    },
    {
      "page": "sample_region_simulation",
      "title": "sample_region_simulation",
      "topics": [
        "sample_region_simulation"
      ]
    },
    {
      "page": "scale_sample",
      "title": "scale_sample",
      "topics": [
        "scale_sample"
      ]
    },
    {
      "page": "shift_sample",
      "title": "shift_sample",
      "topics": [
        "shift_sample"
      ]
    },
    {
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      "title": "sp_dist_euclidean_cpp This function calculates Euclidean distance between cell locations and spot locations.",
      "topics": [
        "sp_dist_euclidean_cpp"
      ]
    },
    {
      "page": "spot_simulate",
      "title": "spot_simulate",
      "topics": [
        "spot_simulate"
      ]
    },
    {
      "page": "tissue_region_simulation",
      "title": "tissue_region_simulation",
      "topics": [
        "tissue_region_simulation"
      ]
    },
    {
      "page": "update_sample_region",
      "title": "update_sample_region",
      "topics": [
        "update_sample_region"
      ]
    },
    {
      "page": "zinb_nll",
      "title": "zinb_nll This function calculates the negative log likelihood of zero-inflated negative binomial distribution.",
      "topics": [
        "zinb_nll"
      ]
    }
  ],
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      "homepage": "http://gcc.gnu.org/",
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    {
      "shlib": "libgomp",
      "package": "libgomp1",
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      "homepage": "http://gcc.gnu.org/",
      "description": "GCC OpenMP (GOMP) support library"
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  "_indexed": true,
  "_nocasepkg": "genescape",
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